The ASPxGridView control can operate only in bound mode. Otherwise, it will not display any data. ASPxGridView can be bound to any standard data source type including: SqlDataSource, ObjectDataSource, XmlDataSource, AccessDataSource, and SiteMapDataSource.
ASPxGridView also supports Database Server Mode - a data binding mode that is specifically designed to work with large data levels: more than 50,000 records. Data is loaded in small portions, and data-aware operations are performed on the server-side to provide quick access to data, even if the sorting, grouping, filtering and summary features are used.